Scientifically Proven Clinical Studies
Our ingredient grades are backed by over 1,078,000 peer-reviewed clinical studies from unbiased third parties including universities, medical associations, and healthcare practitioners.
1,078,000+ Studies
Every ingredient grade is derived from rigorous peer-reviewed clinical research dating back to 1991.
Medical Results & Clinical Evidence
There are over 1,078,000 clinical studies dating back to 1991 for consideration. Every ingredient grade is backed by peer-reviewed clinical studies conducted by unbiased third parties including researchers, colleges, universities, medical associations, hospitals, physicians, scientists, pharmacists, and other healthcare practitioners.
Research DatabaseProbability-Based Grading System
The grade assigned to an ingredient represents the probability that such ingredient will have a positive or negative effect on a large cohort of randomly selected people based upon the findings of the relevant clinical study.
Important: There are no guarantees as to the effectiveness of an individual ingredient in any given person. Individual results may vary based on personal health conditions, genetics, and lifestyle factors.
Our Study Evaluation Criteria
In determining an ingredient grade for an individual condition, our reviewers take into consideration seven critical factors to ensure the highest quality of evidence-based recommendations.
Study Outcome
Positive, negative, or neutral results and their statistical significance
Study Duration
Length of the study period and follow-up assessments
Participant Size
Number of participants to ensure statistical power
Blinding Method
Whether the study was double or triple-blind
Researcher Credentials
Qualifications and expertise of conducting researchers
Funding Source
How and by whom the study was funded
Conflicts of Interest
Any potential biases or conflicts among participants
Patented Efficacy Engine®
Our revolutionary AI-powered system algorithmically calculates product grades by evaluating individual ingredient efficacy in relation to each disease state and condition goal.
The calculation of product grades are algorithmically derived using our patented Efficacy Engine® which evaluates individual ingredient efficacy in relation to each disease state and condition goal and uses AI to compute net product efficacy.
How It WorksCritical Quality Standard
ANY negative ingredient grade (D, E, F) results in a "NO" product grade, ensuring only the highest quality recommendations reach our users.
Access Our Research Database
Explore the clinical studies behind every ingredient grade and discover the science that powers our recommendations.